A group of scientists hailing from Massachusetts General Hospital, Harvard University, and MIT project to illuminate cellular structure located in deep tissues, opaque materials, and all other dense objects. The technique they developed to study these frameworks employs tiny particles that are embedded in material capable of emitting laser light.The team created these “laser particles” in small chopsticks shape whose width measures somewhat a fraction of human hair’s width. These particles are formed from lead iodide perovskite, a special kind of material that is used in solar panels as well. It is efficient enough to trap and absorb light.When the research team lighted up a few particles with laser beams they diffused fluorescent light. However,if they are able to tune these incoming laser beams’ power adhering to a specific threshold, the particles can generate laser light instantly.
The team working on this project was led by Sangyeon Cho, a MIT graduate student, who showcased their ability to stimulate small particles to emit laser light causing creation of images that have six times higher resolution as compared to present fluorescence-based microscopes. Cho says, “That means that if a fluorescence microscope resolution is set at 2 micrometers, our technique can have 300-nanometer resolution—about a sixfold improvement over regular microscopes. The idea is very simple but very powerful and can be useful in many different imaging applications.”
When you show flashlight in a dark room the light seems like a hazy and diffused beam of white light. These stands for a criss-cross haphazard arrangement of various wavelengths and their colors. Contrary to this, the laser light is more monochromatic and focused beam that has a distinct color and frequency. In traditional, fluorescence microscopy, scientists were able to inject a biological tissue sample full of fluorescent dyes. Then they pointed the laser beam via a lens that directed the beam through the tissue lighting up all fluorescent particles that fall in its path.
Filed Under: News